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Article

5-HT2A receptor density is decreased in the at-risk mental state.

Psychopharmacology - 1 Jan 2008

Hurlemann René, Matusch Andreas, Kuhn Kai-Uwe, Berning Julia, Elmenhorst David, Winz Oliver, Kolsch Heike, Zilles Karl, Wagner Michael, Maier Wolfgang, Bauer Andreas

Abstract excerpt

RATIONALE: Current perspectives on the pathophysiology of schizophrenia direct attention to serotonergic (serotonin, 5-HT) dysregulation in the prodrome or at-risk mental state (ARMS). OBJECTIVE: To study the cerebral 5-HT(2A) receptor (5-HT(2A)R) in the ARMS with [(18)F]altanserin positron emission tomography (PET) and a bolus-infusion paradigm. MATERIALS AND METHODS: We quantified the spatial distribution of...

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PMID: 17899021
DOI: 10.1007/s00213-007-0921-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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