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Article

Genetic association of BDNF val66met and GSK-3beta-50T/C polymorphisms with tardive dyskinesia.

Psychiatry and clinical neurosciences - 1 Aug 2009

Park Sung Woo, Lee Jung Goo, Kong Bo Geum, Lee Sun Jung, Lee Chan Hong, Kim Jeong Ik, Kim Young Hoon

Abstract excerpt

AIMS: Neurodegenerative processes may be involved in the pathogenesis of tardive dyskinesia (TD), and a growing body of evidence suggests that brain-derived neurotrophic factor (BDNF) plays a role in both the antipsychotic effects and the pathogenesis of TD. BDNF and glycogen synthase kinase (GSK)-3beta are important in neuronal survival, and thus abnormal regulation of BDNF and GSK-3beta may contribute to TD...

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Source

Identifiers

PMID: 19457211
DOI: 10.1111/j.1440-1819.2009.01976.x

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic association of BDNF val66met and GSK-3beta-50T/C polymorphisms with tardive dyskinesia.PMID 19457211Read ↗

No association between the brain-derived neurotrophic factor gene Val66Met polymorphism and tardive dyskinesia in schizophrenic patients.Semantic proximity Read ↗

Association study of the GSK-3B gene with tardive dyskinesia in European Caucasians.Semantic proximity Read ↗

Genetic study of BDNF, DRD3, and their interaction in tardive dyskinesia.Semantic proximity Read ↗

BDNF Val66Met polymorphism and antipsychotic-induced tardive dyskinesia occurrence and severity: a meta-analysis.Semantic proximity Read ↗

Brain-derived neurotrophic factor levels and its Val66Met gene polymorphism predict tardive dyskinesia treatment response to Ginkgo biloba.Semantic proximity Read ↗

Tardive Dyskinesia Development, Superoxide Dismutase Levels, and Relevant Genetic PolymorphismsSemantic proximity Read ↗

Association analysis of the dopamine D3 receptor gene ser9gly and brain-derived neurotrophic factor gene val66met polymorphisms with antipsychotic-induced persistent tardive dyskinesia and clinical expression in Chinese schizophrenic patients.Semantic proximity Read ↗

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BDNF polymorphisms are associated with schizophrenia onset and positive symptoms.Semantic proximity Read ↗

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