Article
BDNF Val66Met polymorphism and antipsychotic-induced tardive dyskinesia occurrence and severity: a meta-analysis.
Schizophrenia research - 1 Feb 2014
Miura Itaru, Zhang Jian-Ping, Nitta Masahiro, Lencz Todd, Kane John M, Malhotra Anil K, Yabe Hirooki, Correll Christoph U
Abstract excerpt
BACKGROUND: Tardive dyskinesia (TD) is a serious long-term consequence of antipsychotic treatment. Since brain-derived neurotrophic factor (BDNF) has potent neurotrophic activity, genetic alterations in the BDNF gene may affect antipsychotic-induced TD. METHODS: Searching PubMed and Web of Science until 05/31/13, we conducted a systematic review and a meta-analysis of the effects of BDNF Val66Met polymorphism on...
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