Article
No evidence for an association between G protein beta3 subunit gene C825T polymorphism and tardive dyskinesia in schizophrenia.
Human psychopharmacology - 1 Dec 2007
Lee Heon-Jeong, Kang Seung-Gul, Paik Jong-Woo, Lee Moon-Soo, Cho Bang-Hyun, Park Young-Min, Kim Won, Choi Jung-Eun, Jung In-Kwa, Kim Leen, Lee Min-Soo
Abstract excerpt
OBJECTIVE: Tardive dyskinesia (TD) is a long-term adverse effect of antipsychotic. We evaluated candidate functional polymorphism of the G protein beta3 subunit (GNB3) gene for association with drug-induced TD in the Korean schizophrenic patients. METHODS: We investigated whether the C825T polymorphism of the GNB3 gene is associated with the TD in a Korean sample of schizophrenic patients with (n = 83) and...
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