Article
BDNF gene is a genetic risk factor for schizophrenia and is related to the chlorpromazine-induced extrapyramidal syndrome in the Chinese population.
Pharmacogenetics and genomics - 1 Jun 2008
Xu Ming-Qing, St Clair David, Feng Guo-Yin, Lin Zhi-Guang, He Guang, Li Xingwang, He Lin
Abstract excerpt
BACKGROUND: Brain-derived neurotrophic factor (BDNF) belongs to a family of the neurotrophin, which plays important roles in the neurodevelopment of dopaminergic-related systems and interacts with meso-limbic dopaminergic systems involved in the therapeutic response to antipsychotics. Functional experiments have suggested that BDNF may be involved in the etiology of schizophrenia. METHODS AND RESULTS: In this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
