Article
Association analysis of the dopamine D3 receptor gene ser9gly and brain-derived neurotrophic factor gene val66met polymorphisms with antipsychotic-induced persistent tardive dyskinesia and clinical expression in Chinese schizophrenic patients.
Neuromolecular medicine - 1 Jan 2004
Liou Ying-Jay, Liao Ding-Lieh, Chen Jen-Yeu, Wang Ying-Chieh, Lin Chao-Cheng, Bai Ya-Mei, Yu Shun-Chieh, Lin Ming-Wei, Lai I-Ching
Abstract excerpt
The association between the dopamine D3 receptor (DRD3) ser9gly genetic polymorphism and tardive dyskinesia (TD), a serious adverse motor disorder after long-term antipsychotic treatment, has been studied extensively in recent years. However, the existence of inconsistent reports makes the role of the DRD3 ser9gly polymorphism in TD development questionable. In rodent studies, the DRD3 expression could be...
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