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Article

Abeta43 is more frequent than Abeta40 in amyloid plaque cores from Alzheimer disease brains.

Journal of neurochemistry - 1 Jul 2009

Welander Hedvig, Frånberg Jenny, Graff Caroline, Sundström Erik, Winblad Bengt, Tjernberg Lars O

Abstract excerpt

One hallmark of Alzheimer disease (AD) is the extracellular deposition of the amyloid beta-peptide (Abeta) in senile plaques. Two major forms of Abeta are produced, 40 (Abeta40) and 42 (Abeta42) residues long. The most abundant form of Abeta is Abeta40, while Abeta42 is more hydrophobic and more prone to form toxic oligomers and the species of particular importance in early plaque formation. Thus, the length of...

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Source

Identifiers

PMID: 19457079
DOI: 10.1111/j.1471-4159.2009.06170.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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