Article
Association of apolipoprotein E polymorphisms and dietary factors in colorectal cancer.
British journal of cancer - 16 Jun 2009
Mrkonjic M, Chappell E, Pethe V V, Manno M, Daftary D, Greenwood C M, Gallinger S, Zanke B W, Knight J A, Bapat B
Abstract excerpt
ApoE single nucleotide polymorphisms (SNPs) Cys112Arg (Epsilon-4), and Arg158Cys (Epsilon-2) have been implicated in cardiovascular and Alzheimer's disease, but their role in colorectal cancer (CRC) has not been extensively studied. We investigated whether ApoE polymorphisms alone or in combination with dietary factors selectively contribute to mismatch-repair (MMR) proficient (microsatellite stable/low or MSS/L)...
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