Article
Marine ω-3 polyunsaturated fatty acids and risk of colorectal cancer according to microsatellite instability.
Journal of the National Cancer Institute - 1 Apr 2015
Song Mingyang, Nishihara Reiko, Wu Kana, Qian Zhi Rong, Kim Sun A, Sukawa Yasutaka, Mima Kosuke, Inamura Kentaro, Masuda Atsuhiro, Yang Juhong, Fuchs Charles S, Giovannucci Edward L, Ogino Shuji, Chan Andrew T
Abstract excerpt
BACKGROUND: Chronic inflammation is involved in the development of colorectal cancer (CRC) and microsatellite instability (MSI), a distinct phenotype of CRC. Experimental evidence indicates an anti-inflammatory and antineoplastic effect of marine ω-3 polyunsaturated fatty acids (PUFAs). However, epidemiologic data remain inconclusive. METHODS: We investigated whether the association between marine ω-3 PUFAs and...
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