Article
Is the development of adenoma and carcinoma in proximal colon related to apolipoprotein E phenotype?
Gastroenterology - 1 Jun 1996
Kervinen K, Södervik H, Mäkelä J, Lehtola J, Niemi M, Kairaluoma M I, Kesäniemi Y A
Abstract excerpt
BACKGROUND & AIMS: Alterations in plasma lipoprotein levels and bile acid metabolism observed in patients with colorectal adenoma and carcinoma may reflect a genetic background predisposing to altered lipid metabolism and tumors. This study was designed to determine whether the polymorphism of apolipoprotein E, one of the key regulatory proteins in cholesterol metabolism, is associated with proximal or distal...
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