Article
Genotype phenotype correlations in Israeli colorectal cancer patients.
International journal of cancer - 10 Mar 2005
Starinsky Sigal, Figer Arie, Ben-Asher Edna, Geva Ravit, Flex Dov, Fidder Herma H, Zidan Jamal, Lancet Doron, Friedman Eitan
Abstract excerpt
While genetic factors clearly play a key role in colorectal cancer (CRC) pathogenesis and in determining its phenotypic features, the precise genes that involved are largely unknown. To gain insight into these genes, consecutive Israeli CRC patients were genotyped using SNPs from within candidate genes: APC, beta-Catenin, K-RAS, DCC, P16, PTEN, RB1, P15, APOE, ERCC2, P53, MTHFR and hMSH2. Genotyping of...
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