Article
Associations between apoE genotype and colon and rectal cancer.
Carcinogenesis - 1 Aug 2005
Slattery Martha L, Sweeney Carol, Murtaugh Maureen, Ma Khe Ni, Potter John D, Levin Theodore R, Samowitz Wade, Wolff Roger
Abstract excerpt
Apolipoprotein E (apoE) plays a major role in the metabolism of bile acids, cholesterol and triglycerides, and has recently been proposed as being involved in the carcinogenic process. Given the potential role of bile acids in colorectal cancer etiology, it is reasonable that colorectal cancer risk might be modified by apoE genotype. We used data collected from a case-control study of colon cancer (n=1556 cases...
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