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Article

Mutation screening of the glutamate cysteine ligase modifier (GCLM) gene in patients with schizophrenia.

Psychiatric genetics - 1 Aug 2009

Butticaz Christophe, Werge Thomas, Beckmann Jacques S, Cuénod Michel, Do Kim Q, Rivolta Carlo

Abstract excerpt

BACKGROUND: Experimental evidences show that glutathione and its rate-limiting synthesizing enzyme, the glutamate-cysteine ligase (GCL), are involved in the pathogenesis of schizophrenia. Furthermore, genetic association has been previously reported between two single nucleotide polymorphisms lying in noncoding regions of glutamate cysteine ligase modifier (GCLM) gene, which specifies for the modifier subunit of...

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Source

Identifiers

PMID: 19455074
DOI: 10.1097/YPG.0b013e32832cef21

Genes

GCLM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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