Article
Candidate-gene association analysis of response to risperidone in African-American and white patients with schizophrenia.
The pharmacogenomics journal - 1 Oct 2009
Fijal B A, Kinon B J, Kapur S, Stauffer V L, Conley R R, Jamal H H, Kane J M, Witte M M, Houston J P
Abstract excerpt
Clinical trial data were evaluated for the association between 22 single-nucleotide polymorphisms (SNPs) and response in acutely ill patients diagnosed with schizophrenia, schizoaffective disorder or schizophreniform disorder, who were treated with oral risperidone. All patients in the exploratory (78 African Americans) and validation (65 whites) data sets received risperidone 2-6 mg per day over 2-12 weeks. Two...
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