Article
Analysis of gene variants previously associated with iloperidone response in patients with schizophrenia who are treated with risperidone.
The Journal of clinical psychiatry - 1 Mar 2012
Fijal Bonnie A, Stauffer Virginia L, Kinon Bruce J, Conley Robert R, Hoffmann Vicki Poole, Witte Michael M, Zhao Fangyi, Houston John P
Abstract excerpt
OBJECTIVE: We examined 6 single nucleotide polymorphisms (SNPs) previously reported to be associated with response to iloperidone therapy for association with response to risperidone therapy. METHOD: Patients with schizophrenia (DSM-IV) were assessed during 2006 and 2007 for response/nonresponse (defined as ≥ 20%/<20% improvement in Positive and Negative Syndrome Scale [PANSS] total score) after 2 weeks of...
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