Article
The GRM7 gene, early response to risperidone, and schizophrenia: a genome-wide association study and a confirmatory pharmacogenetic analysis.
The pharmacogenomics journal - 1 Mar 2017
Sacchetti E, Magri C, Minelli A, Valsecchi P, Traversa M, Calza S, Vita A, Gennarelli M
Abstract excerpt
The search for biomarkers of response to antipsychotic medications is hindered by difficulties inherent in the topic or related to persistent methodological difficulties, such as high rates of anticipated discontinuation and consequent distortions in the imputation of missing data. Because early response to antipsychotics represents a sufficiently reliable index of the subsequent treatment response in patients...
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