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Article

Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target.

Future oncology (London, England) - 1 May 2009

Lin Jieru E, Li Peng, Pitari Giovanni M, Schulz Stephanie, Waldman Scott A

Abstract excerpt

Colorectal cancer is one of the leading causes of tumor-related morbidity and mortality worldwide. While mechanisms underlying this disease have been elucidated over the past two decades, these molecular insights have failed to translate into efficacious therapy. The oncogenomic view of cancer suggests that terminal transformation reflects the sequential corruption of signal transduction circuits regulating key...

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Identifiers

PMID: 19450179
DOI: 10.2217/fon.09.14
PMCID: PMC2749695

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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