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Article

Guanylyl cyclase C signaling axis and colon cancer prevention.

World journal of gastroenterology - 28 Sept 2016

Pattison Amanda M, Merlino Dante J, Blomain Erik S, Waldman Scott A

Abstract excerpt

Colorectal cancer (CRC) is a major cause of cancer-related mortality and morbidity worldwide. While improved treatments have enhanced overall patient outcome, disease burden encompassing quality of life, cost of care, and patient survival has seen little benefit. Consequently, additional advances in CRC treatments remain important, with an emphasis on preventative measures. Guanylyl cyclase C (GUCY2C), a...

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Source

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Identifiers

PMID: 27688649
DOI: 10.3748/wjg.v22.i36.8070
PMCID: PMC5037076

Genes

GUCY2C
GUCA2A
GUCA2B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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