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Article

Mutational analysis of the PTEN gene in women with premature ovarian failure.

Acta obstetricia et gynecologica Scandinavica - 1 Jan 2009

Shimizu Yoshihiko, Kimura Fuminori, Takebayashi Koichi, Fujiwara Mutsuko, Takakura Kenji, Takahashi Kentaro

Abstract excerpt

Recent studies in mammals have suggested that the phosphatase and tensin homolog deleted on chromosome 10 (PTEN) - phosphatidylinositol-3, 4, 5-trisphosphate pathway in oocytes might be related to the pathogenesis of premature ovarian failure (POF). The aim of this study was to investigate whether mutations of the PTEN gene are present in women with POF. We analyzed the coding region of the PTEN gene in 20 women...

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Identifiers

PMID: 19449221
DOI: 10.1080/00016340902971458

Genes

PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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