Article
Mutational analysis of the PTEN gene in women with premature ovarian failure.
Acta obstetricia et gynecologica Scandinavica - 1 Jan 2009
Shimizu Yoshihiko, Kimura Fuminori, Takebayashi Koichi, Fujiwara Mutsuko, Takakura Kenji, Takahashi Kentaro
Abstract excerpt
Recent studies in mammals have suggested that the phosphatase and tensin homolog deleted on chromosome 10 (PTEN) - phosphatidylinositol-3, 4, 5-trisphosphate pathway in oocytes might be related to the pathogenesis of premature ovarian failure (POF). The aim of this study was to investigate whethe...
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