Article
No association between polymorphisms in PTEN and primary ovarian insufficiency in a Han Chinese population.
Reproductive biology and endocrinology : RB&E - 17 Jun 2015
Zou Weiwei, Wang Binbin, Wang Jing, Zhang Zhiguo, Xu Xiaofeng, Chen Beili, Ma Xu, Cao Yunxia
Abstract excerpt
BACKGROUND: The aim of our study was to investigate the possible relationship between polymorphisms in PTEN (the phosphatase and tensin homolog located on chromosome ten in humans) and POI (primary ovarian insufficiency) in Chinese women. METHODS: Seven tag SNPs (single nucleotide polymorphisms) - rs1234219, rs1903858, rs2299939, rs35352882, rs17107001, and - were chosen from the CHB (Han...