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Article

Genetic changes in the PTEN gene and their association with breast cancer in Pakistan.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011

Baig Ruqia Mehmood, Mahjabeen Ishrat, Sabir Maimoona, Masood Nosheen, Hafeez Saniya, Malik Faraz Arshad, Kayani Mahmood Akhtar

Abstract excerpt

The PTEN gene, a candidate tumor suppressor, is one of the more commonly inactivated and extensively studied genes in cancer. However, few data are available about the role of germ line mutations of this gene in sporadic breast cancer cases. The purpose of this study was to determine extent of involvement of this gene in breast cancer in Pakistan. To test the hypothesis that genetic variations of PTEN play a role...

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Identifiers

PMID: 22320991

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PTEN

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Genetic changes in the PTEN gene and their association with breast cancer in Pakistan.PMID 22320991Read ↗

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