Low-density lipoprotein receptor variants are associated with spontaneous and treatment-induced recovery from hepatitis C virus infection.

doi:10.1016/j.meegid.2009.05.002

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Low-density lipoprotein receptor variants are associated with spontaneous and treatment-induced recovery from hepatitis C virus infection.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2009

Mas Marques Andreas, Mueller Tobias, Welke Justus, Taube Stefan, Sarrazin Christoph, Wiese Manfred, Halangk Juliane, Witt Heiko, Ahlenstiel Golo, Spengler Ulrich, Goebel Uwe, Schott Eckart, Weich Viola, Schlosser Beate, Wasmuth Hermann E, Lammert Frank, Berg Thomas, Schreier Eckart

Abstract excerpt

Low-density lipoprotein receptor (LDLR) is involved in the entry of hepatitis C virus (HCV) in host cells. We investigated whether three single-nucleotide alterations within LDLR might be associated with the course of hepatitis C infection and response to antiviral therapy. We enrolled 651 individuals with chronic HCV infection who had received interferon-based combination therapy, 174 individuals with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Interferons

Share to Logistic Models

Share to Multivariate Analysis

Share to Receptors, LDL

Share to Remission Induction

Share to Remission, Spontaneous

Source

Open in PubMed

Identifiers

PMID: 19446659
DOI: 10.1016/j.meegid.2009.05.002

Genes

LDLR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low-density lipoprotein receptor variants are associated with spontaneous and treatment-induced recovery from hepatitis C virus infection.PMID 19446659Read ↗

Low-density lipoprotein receptor genetic polymorphism in chronic hepatitis C virus Egyptian patients affects treatment response.Semantic proximity Read ↗

Association between LDL-R (exon 8 C.1171 G > A) polymorphisms and response to antiviral therapy in hepatitis C virus infection.Semantic proximity Read ↗

Association of low-density lipoprotein receptor genotypes with hepatitis C viral load.Semantic proximity Read ↗

Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response.Semantic proximity Read ↗

Low-density lipoprotein receptor genotyping enhances the predictive value of IL28B genotype in HIV/hepatitis C virus-coinfected patients.Semantic proximity Read ↗

Effects of the genetic pattern defined by low-density lipoprotein receptor and IL28B genotypes on the outcome of hepatitis C virus infection.Semantic proximity Read ↗

Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.Semantic proximity Read ↗

Scavenger receptor class B member 1 (SCARB1) variants modulate hepatitis C virus replication cycle and viral load.Semantic proximity Read ↗

Single nucleotide polymorphisms of toll-like receptor 7 in hepatitis C virus infection patients from a high-risk chinese population.Semantic proximity Read ↗

Apolipoprotein E allele frequencies in chronic and self-limited hepatitis C suggest a protective effect of APOE4 in the course of hepatitis C virus infection.Semantic proximity Read ↗

Polymorphisms in EGFR and IL28B are associated with spontaneous clearance in an HCV-infected Iranian population.Semantic proximity Read ↗

Correlation of CD81 and SCARB1 polymorphisms on virological responses in Iranian patients with chronic hepatitis C virus genotype 1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.