Article
Polymorphisms in EGFR and IL28B are associated with spontaneous clearance in an HCV-infected Iranian population.
Genes and immunity - 1 Dec 2015
Carapito R, Poustchi H, Kwemou M, Untrau M, Sharifi A H, Merat S, Haj-Sheykholeslami A, Jabbari H, Esmaili S, Michel S, Toussaint J, Le Gentil M, Ansari-Moghaddam A, Radosavljevic M, Etemadi A, Georgel P, Malekzadeh R, Bahram S
Abstract excerpt
Although most hepatitis C virus (HCV)-infected individuals develop chronic infection, about 25% of them are able to clear the virus spontaneously without any therapeutic intervention. The aim of the present study was to identify genes associated with spontaneous HCV clearance in a population of Iranian patients. We genotyped 110 single-nucleotide polymorphisms (SNPs) in 59 selected--candidate--genes in a cohort...
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