Article
Association between LDL-R (exon 8 C.1171 G > A) polymorphisms and response to antiviral therapy in hepatitis C virus infection.
Scientific reports - 21 Feb 2026
Shikhoun Mohey Eldin Hassan, Ibrahim Hesham A M, Abeed Ahmed Abdou O
Abstract excerpt
The entry of the hepatitis C virus (HCV) into liver cells is closely associated with its interaction with the low-density lipoprotein receptor (LDL-R), which plays a crucial role in facilitating viral uptake. This study aimed to investigate the association between the LDL-R (exon 8 C.1171 G/A) gene polymorphism and response to antiviral therapy in patients infected with HCV. Participants were divided into three...
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