Article
Low-density lipoprotein receptor genotyping enhances the predictive value of IL28B genotype in HIV/hepatitis C virus-coinfected patients.
AIDS (London, England) - 17 Jul 2011
Pineda Juan A, Caruz Antonio, Di Lello Federico A, Camacho Angela, Mesa Pilar, Neukam Karin, Rivero-juárez Antonio, Macías Juan, Gómez-Mateos Jesús, Rivero Antonio
Abstract excerpt
OBJECTIVE: The aims of this study were to appraise the predictive value of variations in a single-nucleotide polymorphism (SNP) in the low-density lipoprotein receptor (LDLR) gene for sustained virological response (SVR) to pegylated interferon (Peg-IFN) and ribavirin (RBV), as well as to analyze the relationship between LDLR genotype and other predictors of SVR, particularly IL28B genotype, in patients...
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