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Article

Association of low-density lipoprotein receptor genotypes with hepatitis C viral load.

Genes and immunity - 1 Jan 2014

Caruz A, Neukam K, Rivero-Juárez A, Herrero R, Real L M, Camacho A, Barreiro P, Labarga P, Rivero A, Pineda J A

Abstract excerpt

Several data suggest that low-density lipoprotein receptor (LDLR) is a co-receptor for hepatitis C virus (HCV). Soluble LDLR can inhibit HCV infectivity; greater plasma low-density lipoprotein levels are associated with treatment success; LDLR genotypes have a synergistic impact on the likelihood of achieving SVR with Peg-IFN plus RBV, as well as on viral kinetics after starting treatment. The objective of this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24173146
DOI: 10.1038/gene.2013.56

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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