Article
Interleukin-1Ra rs2234663 and Interleukin-4 rs79071878 Polymorphisms in Familial Mediterranean Fever.
Gene - 15 May 2016
Nursal Ayse Feyda, Tekcan Akin, Kaya Suheyla Uzun, Sezer Ozlem, Yigit Serbulent
Abstract excerpt
OBJECTIVE: Familial Mediterranean Fever (FMF) is an autosomal recessively inherited auto inflammatory disorder. MEFV gene, causing FMF, encodes pyrin that is associated with the interleukin-1 (IL-1) related inflammation cascade. The aim of this study was to investigate the relationship of interleukin-1 receptor antagonist (IL-1Ra) and interleukin-4 (IL-4) polymorphisms with the risk of FMF in the Turkish...
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