Article
Tumor necrosis factor-α gene polymorphisms in FMF and their association with amyloidosis.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Nov 2012
Bonyadi Mortaza, Bahrami Salahadin, Jahanafrooz Zohreh, Dastgiri Saeed
Abstract excerpt
Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by periodic provocative attacks of fever with peritonitis, pleuritis, arthritis, or eriseplemya. Tumor necrosis factor-α (TNF-α) plays an important role in the regulation of the immune response as a part of the cytokine network, including activation of macrophages and apoptosis. We investigated the possible association of TNF-α...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.