Article
Serum IL 4 and its gene polymorphism (rs79071878) in Egyptian children with familial Mediterranean fever.
Clinical rheumatology - 1 Dec 2018
Marzouk Huda, Farag Yomna, El-Hanafi Hadeel M, Ibrahim Eman
Abstract excerpt
Familial Mediterranean fever (FMF) is an autoinflammatory disorder. It is caused by mutations in the MEFV gene encoding the pyrin protein, which regulates the innate inflammatory response. The aim of the current study was to investigate the relationship between serum Interleukin-4 (IL-4) and its gene polymorphism, namely rs79071878, and FMF occurrence, severity, and response to treatment in Egyptian children...
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