Patterns of chromosomal imbalances in muscle invasive bladder cancer.

doi:10.3892/ijo.17.5.1025

Article

Patterns of chromosomal imbalances in muscle invasive bladder cancer.

1 Nov 2000

Abstract excerpt

Cytogenetic investigations of bladder cancer suggested that development and progression is characterized by specific chromosomal aberrations. In order to identify genetic changes linked to muscle invasive tumors and metastatic growth we analyzed 67 bladder carcinomas (30 pT1 and 37 pT2-4) by means of comparative genomic hybridization (CGH). The most frequent changes were gains of chromosome 1q (54%), 8q (54%),...

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