Article
Genomic Predictors of Good Outcome, Recurrence, or Progression in High-Grade T1 Non-Muscle-Invasive Bladder Cancer.
Cancer research - 15 Oct 2020
Bellmunt Joaquim, Kim Jaegil, Reardon Brendan, Perera-Bel Júlia, Orsola Anna, Rodriguez-Vida Alejo, Wankowicz Stephanie A, Bowden Michaela, Barletta Justine A, Morote Juan, de Torres Inés, Juanpere Nuria, Lloreta-Trull Josep, Hernandez Silvia, Mouw Kent W, Taplin Mary-Ellen, Cejas Paloma, Long Henry W, Van Allen Eliezer M, Getz Gad, Kwiatkowski David J
Abstract excerpt
High-grade T1 (HGT1) bladder cancer is the highest risk subtype of non-muscle-invasive bladder cancer with unpredictable outcome and poorly understood risk factors. Here, we examined the association of somatic mutation profiles with nonrecurrent disease (GO, good outcome), recurrence (R), or progression (PD) in a cohort of HGT1 patients. Exome sequencing was performed on 62 HGT1 and 15 matched normal tissue...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
