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Article

Novel tumor subgroups of urothelial carcinoma of the bladder defined by integrated genomic analysis.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2012

Hurst Carolyn D, Platt Fiona M, Taylor Claire F, Knowles Margaret A

Abstract excerpt

PURPOSE: There is a need for improved subclassification of urothelial carcinoma (UC) at diagnosis. A major aim of this study was to search for novel genomic subgroups. EXPERIMENTAL DESIGN: We assessed 160 tumors for genome-wide copy number alterations and mutation in genes implicated in UC. These comprised all tumor grades and stages and included 49 high-grade stage T1 (T1G3) tumors. RESULTS: Our findings point...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22932667
DOI: 10.1158/1078-0432.CCR-12-1807
PMCID: PMC5081094

Genes

FGFR3
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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