Article
Bladder cancer stage and outcome by array-based comparative genomic hybridization.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2005
Blaveri Ekaterini, Brewer Jeremy L, Roydasgupta Ritu, Fridlyand Jane, DeVries Sandy, Koppie Theresa, Pejavar Sunanda, Mehta Kshama, Carroll Peter, Simko Jeff P, Waldman Frederic M
Abstract excerpt
PURPOSE: Bladder carcinogenesis is believed to follow alternative pathways of disease progression driven by an accumulation of genetic alterations. The purpose of this study was to evaluate associations between measures of genomic instability and bladder cancer clinical phenotype. EXPERIMENTAL DESIGN: Genome-wide copy number profiles were obtained for 98 bladder tumors of diverse stages (29 pT(a), 14 pT1, 55...
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