Article
High-density single nucleotide polymorphism array defines novel stage and location-dependent allelic imbalances in human bladder tumors.
Cancer research - 1 Jan 2005
Koed Karen, Wiuf Carsten, Christensen Lise-Lotte, Wikman Friedrik P, Zieger Karsten, Møller Klaus, von der Maase Hans, Orntoft Torben F
Abstract excerpt
Bladder cancer is a common disease characterized by multiple recurrences and an invasive disease course in more than 10% of patients. It is of monoclonal or oligoclonal origin and genomic instability has been shown at certain loci. We used a 10,000 single nucleotide polymorphism (SNP) array with an average of 2,700 heterozygous SNPs to detect allelic imbalances (AI) in 37 microdissected bladder tumors from 17...
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