Article
Are bone mineral density loci associated with hip osteoporotic fractures? A validation study on previously reported genome-wide association loci in a Chinese population.
Genetics and molecular research : GMR - 31 Jan 2012
Guo Y, Wang J-T, Liu H, Li M, Yang T-L, Zhang X-W, Liu Y-Z, Tian Q, Deng H-W
Abstract excerpt
Osteoporosis is a heritable disease characterized mainly by low bone mineral density (BMD) and/or osteoporotic fractures (OF). Most genome-wide association studies on osteoporosis have focused on BMD, whereas little effort has been expended to identify genetic variants directly linked to OF. To determine whether BMD-loci are also associated with OF risk, we performed a validation study to examine 23...
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