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Article

Genetic and epigenetic heterogeneity in cancer: a genome-centric perspective.

Journal of cellular physiology - 1 Sept 2009

Heng Henry H Q, Bremer Steven W, Stevens Joshua B, Ye Karen J, Liu Guo, Ye Christine J

Abstract excerpt

Genetic and epigenetic heterogeneity (the main form of non-genetic heterogeneity) are key elements in cancer progression and drug resistance, as they provide needed population diversity, complexity, and robustness. Despite drastically increased evidence of multiple levels of heterogeneity in cancer, the general approach has been to eliminate the "noise" of heterogeneity to establish genetic and epigenetic...

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PMID: 19441078
DOI: 10.1002/jcp.21799

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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