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Article

Cancer genome sequencing: the challenges ahead.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Aug 2007

Heng Henry H Q

Abstract excerpt

A major challenge for The Cancer Genome Atlas (TCGA) Project is solving the high level of genetic and epigenetic heterogeneity of cancer. For the majority of solid tumors, evolution patterns are stochastic and the end products are unpredictable, in contrast to the relatively predictable stepwise patterns classically described in many hematological cancers. Further, it is genome aberrations, rather than gene...

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PMID: 17621658
DOI: 10.1002/bies.20610

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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