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Article

Strain-specific phenotypes of airway inflammation and bronchial hyperresponsiveness induced by epicutaneous allergen sensitization in BALB/c and C57BL/6 mice.

International archives of allergy and immunology - 1 Jan 2010

Kodama Motohiro, Asano Koichiro, Oguma Tsuyoshi, Kagawa Shizuko, Tomomatsu Katsuyoshi, Wakaki Misa, Takihara Takahisa, Ueda Soichiro, Ohmori Nao, Ogura Hiromi, Miyata Jun, Tanaka Kyuto, Kamiishi Nobufumi, Fukunaga Koichi, Sayama Koichi, Ikeda Eiji, Miyasho Taku, Ishizaka Akitoshi

Abstract excerpt

BACKGROUND: Allergen sensitization through a disrupted skin barrier appears to play a prominent role in the development of atopic diseases, including allergic asthma. The role of the genetic background in immunological and physiological phenotypes induced by epicutaneous sensitization is undetermined. METHODS: BALB/c and C57BL/6 mice were sensitized either epicutaneously by patch application of ovalbumin (OVA) or...

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PMID: 20523066
DOI: 10.1159/000312128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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