Article
Establishing the phenotype in novel acute and chronic murine models of allergic asthma.
International immunopharmacology - 1 May 2008
Fernandez-Rodriguez Sofia, Ford William R, Broadley Kenneth J, Kidd Emma J
Abstract excerpt
Allergic asthma is a chronic disease of the airways, with superimposed acute inflammatory episodes which correspond to exacerbations of asthma. Two novel models of allergic asthma have been developed in mice receiving the same allergen sensitisation, but with acute or chronic allergen exposures, the latter to mimic the human situation more closely. Ovalbumin-sensitised mice were challenged by ovalbumin inhalation...
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