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Article

Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.

European heart journal - 1 Jul 2009

Murray Anna, Cluett Christie, Bandinelli Stefania, Corsi Anna Maria, Ferrucci Luigi, Guralnik Jack, Singleton Andrew, Frayling Timothy, Melzer David

Abstract excerpt

AIMS: There are a large number of common genetic variants that have been robustly associated with low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, or triglyceride concentrations. The majority of these have been identified or confirmed in recent genome-wide association studies, but few studies have assessed the combined effect of known lipid variants. We hypothesized that...

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Source

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Identifiers

PMID: 19435741
DOI: 10.1093/eurheartj/ehp161
PMCID: PMC2709886

Genes

APOE
CETP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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