Article
Genetics of Triglyceride-Rich Lipoproteins Guide Identification of Pharmacotherapy for Cardiovascular Risk Reduction.
Cardiovascular drugs and therapy - 1 Jun 2021
Shaik Aleesha, Rosenson Robert S
Abstract excerpt
OBJECTIVE: Despite aggressive reduction of low-density lipoprotein cholesterol (LDL-C), there is a residual risk of cardiovascular disease (CVD). Hypertriglyceridemia is known to be associated with increased CVD risk, independently of LDL-C. Triglycerides are one component of the heterogenous class of triglyceride-rich lipoproteins (TGRLs). METHODS/RESULTS: Growing evidence from biology, epidemiology, and...
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