Article
Transcriptional silencing and reactivation in transgenic zebrafish.
Genetics - 1 Jul 2009
Goll Mary G, Anderson Ryan, Stainier Didier Y R, Spradling Allan C, Halpern Marnie E
Abstract excerpt
Epigenetic regulation of transcriptional silencing is essential for normal development. Despite its importance, in vivo systems for examining gene silencing at cellular resolution have been lacking in developing vertebrates. We describe a transgenic approach that allows monitoring of an epigenetically regulated fluorescent reporter in developing zebrafish and their progeny. Using a self-reporting Gal4-VP16...
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