Article
Transgene-mediated skeletal phenotypic variation in zebrafish.
Journal of fish biology - 1 Apr 2021
Kimmel Charles B, Wind Alexander L, Oliva Whitney, Ahlquist Samuel D, Walker Charline, Dowd John, Blanco-Sánchez Bernardo, Titus Tom A, Batzel Peter, Talbot Jared C, Postlethwait John H, Nichols James T
Abstract excerpt
When considering relationships between genotype and phenotype we frequently ignore the fact that the genome of a typical animal, notably including that of a fish and a human, harbours a huge amount of foreign DNA. Such DNA, in the form of transposable elements, can affect genome function in a major way, and transgene biology needs to be included in our understanding of the genome. Here we examine an unexpected...
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