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Article

Targeted gene expression in transgenic Xenopus using the binary Gal4-UAS system.

Proceedings of the National Academy of Sciences of the United States of America - 5 Feb 2002

Hartley Katharine O, Nutt Stephen L, Amaya Enrique

Abstract excerpt

The transgenic technique in Xenopus allows one to misexpress genes in a temporally and spatially controlled manner. However, this system suffers from two experimental limitations. First, the restriction enzyme-mediated integration procedure relies on chromosomal damage, resulting in a percentage of embryos failing to develop normally. Second, every transgenic embryo has unique sites of integration and unique...

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Identifiers

PMID: 11818539
DOI: 10.1073/pnas.022646899
PMCID: PMC122198

Genes

BMP4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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