Article
Protein kinase C epsilon subcellular localization domains and proteolytic degradation sites. A model for protein kinase C conformational changes.
The Journal of biological chemistry - 18 Aug 1995
Lehel C, Oláh Z, Jakab G, Szállási Z, Petrovics G, Harta G, Blumberg P M, Anderson W B
Abstract excerpt
Protein kinase C (PCK) epsilon has been found to have unique properties among the PCK isozymes in terms of its membrane association, oncogenic potential, and substrate specificity. Recently we have demonstrated that PKC epsilon localizes to the Golgi network via its zinc finger domain and that bo...
Topics
- 3T3 Cells
- Animals
- Base Sequence
- Biological Transport
- Blotting, Western
- Hydrolysis
- Immunohistochemistry
- Isoenzymes
- Mice
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Protein Conformation
- Protein Kinase C
- Protein Kinase C-epsilon