Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fluorescence detection of single-nucleotide polymorphisms with a single, self-complementary, triple-stem DNA probe.

Angewandte Chemie (International ed. in English) - 1 Jan 2009

Xiao Yi, Plakos Kory J I, Lou Xinhui, White Ryan J, Qian Jiangrong, Plaxco Kevin W, Soh H Tom

Abstract excerpt

Singled out for its singularity: In a single-step, single-component, fluorescence-based method for the detection of single-nucleotide polymorphisms at room temperature, the sensor is comprised of a single, self-complementary DNA strand that forms a triple-stem structure. The large conformational change that occurs upon binding to perfectly matched (PM) targets results in a significant increase in fluorescence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA Probes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fluorescent Dyes

Share to Polymorphism, Single Nucleotide

Share to Spectrometry, Fluorescence

Share to Thermodynamics

Source

Open in PubMed Open full text

Identifiers

PMID: 19431180
DOI: 10.1002/anie.200900369
PMCID: PMC3053031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fluorescence detection of single-nucleotide polymorphisms with a single, self-complementary, triple-stem DNA probe.PMID 19431180Read ↗

An electrochemical sensor for single nucleotide polymorphism detection in serum based on a triple-stem DNA probe.Semantic proximity Read ↗

DNA-probes for the highly sensitive identification of single nucleotide polymorphism using single-molecule spectroscopy.Semantic proximity Read ↗

A star-shaped DNA probe based on strand displacement for universal and multiplexed fluorometric detection of genetic variations.Semantic proximity Read ↗

Single-tube genotyping without oligonucleotide probes.Semantic proximity Read ↗

Invader assay-induced catalytic assembly of multi-DNAzyme junctions for sensitive detection of single nucleotide polymorphisms.Semantic proximity Read ↗

Single-Labeled Oligonucleotides Showing Fluorescence Changes Upon Hybridization with Target Nucleic Acids.Semantic proximity Read ↗

Fluorescent detection of single nucleotide polymorphism utilizing a hairpin DNA containing a nucleotide base analog pyrrolo-deoxycytidine as a fluorescent probe.Semantic proximity Read ↗

Molecular-beacon-based tricomponent probe for SNP analysis in folded nucleic acids.Semantic proximity Read ↗

Fluorescence detection of single-nucleotide polymorphism with single-strand triplex-forming DNA probes.Semantic proximity Read ↗

Highly sensitive electrochemiluminescence detection of single-nucleotide polymorphisms based on isothermal cycle-assisted triple-stem probe with dual-nanoparticle label.Semantic proximity Read ↗

An exciplex-based, target-assembled fluorescence system with inherently low background to probe for specific nucleic acid sequences.Semantic proximity Read ↗

A homogeneous fluorescence assay for PCR amplicons: its application to real-time, single-tube genotyping.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.