Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA-probes for the highly sensitive identification of single nucleotide polymorphism using single-molecule spectroscopy.

FEBS letters - 17 Apr 2007

Friedrich Achim, Hoheisel Jörg D, Marmé Nicole, Knemeyer Jens-Peter

Abstract excerpt

This article presents a new, highly sensitive method for the identification of single nucleotide polymorphisms (SNPs) in homogeneous solutions using fluorescently labeled hairpin-structured oligonucleotides (smart probes) and fluorescence single-molecule spectroscopy. While the hairpin probe is closed, fluorescence intensity is quenched due to close contact between the chromophore and several guanosine residues....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA Probes
Share to Nucleic Acid Hybridization

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Share to Spectrometry, Fluorescence

Source

Identifiers

PMID: 17399707
DOI: 10.1016/j.febslet.2007.03.031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA-probes for the highly sensitive identification of single nucleotide polymorphism using single-molecule spectroscopy.PMID 17399707Read ↗

Single-Labeled Oligonucleotides Showing Fluorescence Changes Upon Hybridization with Target Nucleic Acids.Semantic proximity Read ↗

Emerging technologies for hybridization based single nucleotide polymorphism detection.Semantic proximity Read ↗

Identification of single-point mutations in mycobacterial 16S rRNA sequences by confocal single-molecule fluorescence spectroscopy.Semantic proximity Read ↗

Visual detection of single-nucleotide polymorphism with hairpin oligonucleotide-functionalized gold nanoparticles.Semantic proximity Read ↗

Detection of SNP-containing human DNA sequences using a split sensor with a universal molecular beacon reporter.Semantic proximity Read ↗

Electroanalysis of single-nucleotide polymorphism by hairpin DNA architectures.Semantic proximity Read ↗

Detection of single-nucleotide polymorphisms using gold nanoparticles and single-strand-specific nucleases.Semantic proximity Read ↗

Fluorescence detection of single-nucleotide polymorphisms with a single, self-complementary, triple-stem DNA probe.Semantic proximity Read ↗

Fluorescent detection of single nucleotide polymorphism utilizing a hairpin DNA containing a nucleotide base analog pyrrolo-deoxycytidine as a fluorescent probe.Semantic proximity Read ↗

Single molecule based SNP detection using designed DNA carriers and solid-state nanopores.Semantic proximity Read ↗

Twin probes as a novel tool for the detection of single-nucleotide polymorphisms.Semantic proximity Read ↗

Fluorescence detection of single nucleotide polymorphisms using a universal molecular beacon.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.