Article
Uridine diphosphoglucuronosyltransferase 1A7 gene polymorphism and susceptibility to chromosomal damage among polycyclic aromatic hydrocarbons exposed workers.
Journal of occupational and environmental medicine - 1 Jun 2009
Wang Yadong, Duan Huawei, Dai Yufei, Bin Ping, Cheng Juan, Pan Zufei, Huang Chuanfeng, Leng Shuguang, Chen Wen, Zheng Yuxin
Abstract excerpt
OBJECTIVE: The aim of this study was to explore the relationship between UGT1A7 gene polymorphisms and susceptibility to chromosomal damage among polycyclic aromatic hydrocarbons (PAH)-exposed workers. METHODS: Blood and urine samples of 140 PAH-exposed workers and 66 non-PAH-exposed workers were collected. The polymorphisms of UGT1A7, cytokinesis-block micronucleus (CBMN) and 1-hydroxypyrene were analyzed....
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