Article
Modulation of DNA repair capacity by ataxia telangiectasia mutated gene polymorphisms among polycyclic aromatic hydrocarbons-exposed workers.
Toxicological sciences : an official journal of the Society of Toxicology - 1 Nov 2011
Wang Yadong, Cheng Juan, Li Daochuan, Duan Huawei, Yang Haijun, Bin Ping, Dai Yufei, Huang Chuanfeng, Liang Xuemiao, Leng Shuguang, Chen Wen, Zheng Yuxin
Abstract excerpt
The purpose of this study was to address the association between the ataxia telangiectasia mutated (ATM) gene polymorphisms and susceptibility to DNA repair capacity (DRC) among polycyclic aromatic hydrocarbons (PAHs)-exposed workers. Polymorphisms of ATM were genotyped. DRC was determined by comet assay. Chromosomal damage was detected by cytokinesis-block micronucleus (CBMN) assay. Flow cytometry was used to...
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