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Article

[Mutations of drug target molecules in Pneumocystis jirovecii isolates and future investigations].

Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology - 1 Jan 2009

Takahashi Takashi

Abstract excerpt

Pneumocystis (Pc) jirovecii causes severe interstitial pneumonia in patients with immunodeficiency, in whom this fungus adheres with type-I alveolar epithelial cells. Therefore, it is important to perform quick diagnosis and treatment for Pc pneumonia (PcP). In general, a combination of two antifolate agents, sulfamethoxazole (inhibition of dihydropteroate synthase (DHPS)) and trimethoprim (inhibition of...

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Identifiers

PMID: 19430180
DOI: 10.3314/jjmm.50.067

Genes

DHPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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